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Structure and expression of the gene responsible for the triplet repeat disorder, dentatorubral and pallidoluysian atrophy (DRPLA)

✍ Scribed by Shirayama, Takefumi; Tadokoro, Keiko; Inoue, Tadashi; Yamada, Masao; Nagafuchi, Shigeo; Yanagisawa, Hiroko; Ohsaki, Emiko


Book ID
109918245
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
619 KB
Volume
8
Category
Article
ISSN
1061-4036

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Regional and cellular expression of the
✍ K. Nishiyama; K. Nakamura; Dr S. Murayama; M. Yamada; I. Kanazawa πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 745 KB

Dentatorubral-pallidoluysian atrophy is an autosomal dominant neurodegenerative disorder characterized by dementia and spinocerebellar degeneration. Recently, part of the gene responsible for this disorder was cloned containing a CAG repeat, and predominant neuronal expression of the gene was proved