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Structure and enzymology of a death-associated protein kinase

✍ Scribed by Linda J Van Eldik


Book ID
117341075
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
66 KB
Volume
23
Category
Article
ISSN
0165-6147

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Death-associated protein kinase (DAP-kinase) is Ca 2Ψ‰ / calmodulin-dependent serine/threonine kinase that contains ankyrin repeats and the death domain. It has been isolated as a positive mediator of interferon-β₯induced apoptotic cell death of HeLa cells. In order to reveal the physiological role of