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Structure and Dynamics of the Homodimeric Dynein Light Chain km23

✍ Scribed by Udayar Ilangovan; Wei Ding; Yan Zhong; Christina L. Wilson; Jay C. Groppe; James T. Trbovich; Jorge Zúñiga; Borries Demeler; Qian Tang; Guofeng Gao; Kathleen M. Mulder; Andrew P. Hinck

Book ID
116662322
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
832 KB
Volume
352
Category
Article
ISSN
0022-2836

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Overexpression of the dynein light chain
Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase
✍ Nageswara R. Pulipati; Qunyan Jin; Xin Liu; Baodong Sun; Yan Zhao; Manoj K. Pand 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 938 KB

## Abstract km23‐1 is a dynein light chain that was identified as a TGFβ receptor‐interacting protein. To investigate whether km23‐1 controls human ovarian carcinoma cell (HOCC) growth, we established a tet‐off inducible expression system in SKOV‐3 cells in which the expression of km23‐1 is induced