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Structure and Dynamics of the Antibiotic Peptide PGLa in Membranes by Solution and Solid-State Nuclear Magnetic Resonance Spectroscopy

✍ Scribed by Bechinger, B.; Zasloff, M.; Opella, S.J.


Book ID
119411302
Publisher
Biophysical Society
Year
1998
Tongue
English
Weight
208 KB
Volume
74
Category
Article
ISSN
0006-3495

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✍ Burkhard Bechinger; Michael Zasloff; Stanley J. Opella πŸ“‚ Article πŸ“… 1993 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 729 KB

## Abstract Magainin 2 is a 23‐residue peptide that forms an amphipathic __Ξ±__‐helix in membrane environments. It functions as an antibiotic and is known to disrupt the electrochemical gradients across the cell membranes of many bacteria, fungi, and some tumor cells, although it does not lyse red b