Structure and orientation of the antibio
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Burkhard Bechinger; Michael Zasloff; Stanley J. Opella
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Article
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1993
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Cold Spring Harbor Laboratory Press
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English
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## Abstract Magainin 2 is a 23βresidue peptide that forms an amphipathic __Ξ±__βhelix in membrane environments. It functions as an antibiotic and is known to disrupt the electrochemical gradients across the cell membranes of many bacteria, fungi, and some tumor cells, although it does not lyse red b