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Structure and Dynamics of Molten Globular Intermediates Encountered during the Unfolding of Barstar

✍ Scribed by Sarkar, Saswata S.; Udgaonkar, Jayant B.; Krishnamoorthy, Guruswamy


Book ID
122296834
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
62 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract New experimental results show that either gain or loss of close packing can be observed as a discrete step in protein folding or unfolding reactions. This finding poses a significant challenge to the conventional two‐state model of protein folding. Results of interest involve dry molten