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Structure and conformation of an antidepressant drug, nitroxazepine hydrochloride monohydrate

✍ Scribed by Usha, R. ;Bhadbhade, M. M. ;Venkatesan, K. ;Nagarajan, K. ;David, J.


Book ID
114528614
Publisher
International Union of Crystallography
Year
1982
Weight
408 KB
Volume
38
Category
Article
ISSN
0567-7408

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Conformation and intermolecular interati
✍ Sudha Srivastava; Ratna S. Phadke; Girjesh Govil; K. Nagarajan πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 479 KB

Complete assignments of the proton magnetic resonance spectra of nitroxazepine and imipramine have been made using 1D and 2D techniques. The drugs are found to aggregate through stacking intereactions between the tricyclic moieties at higher concentrations in aqueous solutions. The changes in the ch