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Structure and Catalytic Mechanism of a SET Domain Protein Methyltransferase

โœ Scribed by Raymond C. Trievel; Bridgette M. Beach; Lynnette M.A. Dirk; Robert L. Houtz; James H. Hurley


Book ID
117269275
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
858 KB
Volume
111
Category
Article
ISSN
0092-8674

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Structure and Catalytic Mechanism of a S
โœ Raymond C. Trievel; Bridgette M. Beach; Lynnette M.A. Dirk; Robert L. Houtz; Jam ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 858 KB

Protein lysine methylation by SET domain enzymes regulates chromatin structure, gene silencing, transcriptional activation, plant metabolism, and other processes. The 2.6 A resolution structure of Rubisco large subunit methyltransferase in a pseudo-bisubstrate complex with S-adenosylhomocysteine and