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Structure and Biosynthesis of Mutolide, a Novel Macrolide from a UV Mutant of the Fungus F-24′707

✍ Scribed by Helge Björn Bode; Martina Walker; Axel Zeeck

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
246 KB
Volume
2000
Category
Article
ISSN
1434-193X

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✦ Synopsis

The 14-membered macrolide, mutolide (1), was discovered by chemical screening of the culture broth of the fungus F-24Ј707y, obtained after UV mutagenesis of the wild type strain, which normally produces the spirobisnaphthalene cladospirone bisepoxide (2). The structure of 1 was established by detailed spectroscopic analysis, X-ray analysis and deriv-

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