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Structure and activity of interleukin 5, a key mediator of asthmatic inflammation

✍ Scribed by Timothy N.C. Wells; Christian Y. Arod; Pierre Graber; Anne M. Hassel; Steven R. Jordan; Michael V. Milburn; Francois Talabot; Amanda E.I. Proudfoot

Book ID
116172728
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
165 KB
Volume
6
Category
Article
ISSN
1043-4666

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## Abstract ## Background Asthma is a chronic disease characterized by airway inflammation caused by the dysregulated production of cytokines secreted by allergen‐specific type 2 T helper (Th2) cells. Although the Th1‐promoting cytokine, interleukin (IL)‐12, is capable of inhibiting Th2‐driven all