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Structure activity relationships using molecular connectivity indices with principal component analysis

✍ Scribed by Lawrence P. Burkhard; Anders W. Andren; David E. Armstrong


Book ID
119021361
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
457 KB
Volume
12
Category
Article
ISSN
0045-6535

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Quantitative relationships between the structure and pharmacokinetic parameters of several compounds have been derived using the molecular connectivity approach. The correlation coefficients of equations obtained using the Chi indices (x) as predictor parameters were compared favorably with those ob