Structure–activity relationships of inve
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Willem Soudijn; Ineke van Wijngaarden; Adriaan P. Ijzerman
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Article
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2005
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John Wiley and Sons
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English
⚖ 384 KB
## Abstract It has been recently established that G‐protein‐coupled receptors (GPCRs) can be constitutively active, i.e., they can be active in the absence of an agonist. This activity can be inhibited by so‐called inverse agonists. For a number of GPCRs, such inverse agonists have been developed a