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Structure-activity relationships of cyclic β-casomorphin-5 analogues

✍ Scribed by Ralf Schmidt; Klaus Neubert; Alfred Barth; Claus Liebmann; Martin Schnittler; Nga N. Chung; Peter W. Schiller

Book ID: 119142489
Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 495 KB
Volume: 12
Category: Article
ISSN: 0196-9781
DOI: 10.1016/0196-9781(91)90191-q

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## Abstract A theoretical conformational analysis (molecular mechanics study) of nine cyclic tetrapeptides, structurally related to the highly μ‐receptor‐selective dermorphin analogue , was performed. These compounds display considerable diversity in their μ‐receptor affinity and selectivity. A sys