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Structure-activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin

✍ Scribed by W.C. Chan; M. Leyland; J. Clark; H.M. Dodd; L.-Y. Lian; M.J. Gasson; B.W. Bycroft; G.C.K. Roberts


Book ID
115932582
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
450 KB
Volume
390
Category
Article
ISSN
0014-5793

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Structure-activity relationship of indol
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## Abstract A series of Trp and Arg analogs of antibacterial indolicidin (Ind) was synthesized and the antimicrobial and hemolytic activities were investigated. [L^9^]Ind, [L^11^]Ind, [K^8^,L^9^]Ind and [K^6, 8^,L^9^]Ind showed desirable characteristics, exhibiting negligible hemolytic activity whi