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Structure activity relationship of phosphoramidon derivatives for in vivo endothelin-converting-enzyme inhibition

โœ Scribed by M. Bigaud; B. Hauss; C. Schalk; MF Jauch; H. D'Orchymont


Book ID
115274043
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
546 KB
Volume
8
Category
Article
ISSN
0767-3981

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The purpose of the present study was to contrast a commonly used ACE inhibitor (enalaprilat) with a novel ACE inhibitor (trandolaprilat) in their ability to inhibit 1) pulmonary capillary endothelialbound ACE activity in vivo, 2) arterial pressure responses to i.v. angiotensin I and bradykinin, and