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Structure-activity relationship of a bitter diketopiperazine revisited

✍ Scribed by Murray Goodman; Piero Andrea Temussi

Publisher
Wiley (John Wiley & Sons)
Year
1985
Tongue
English
Weight
241 KB
Volume
24
Category
Article
ISSN
0006-3525

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✦ Synopsis

Bitter and sweet tastes are linked by a close relationship. It has long been known that seemingly minor modifications in the chemical constitution of many sweet molecules can lead to a bitter taste.' Striking examples are provided by several hydrophobic amino acids, whose R antipodes are sweet, where-

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