✦ LIBER ✦

Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues

✍ Scribed by SCHWARCZ, R; SCHOLZ, D; COYLE, J

Book ID: 121978283
Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 914 KB
Volume: 17
Category: Article
ISSN: 0028-3908
DOI: 10.1016/0028-3908(78)90127-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The actions of cyclopentane analogues of

The actions of cyclopentane analogues of glutamic acid at binding sites for kainic and glutamic acids

✍ H. McLennan; K. Curry 📂 Article 📅 1988 🏛 Springer-Verlag 🌐 English ⚖ 259 KB

The activation of glutamate receptors by

The activation of glutamate receptors by kainic acid and domoic acid

✍ David R. Hampson; Jerrie Lynn Manalo 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB

The neurotoxins kainic acid and domoic acid are potent agonists at the kainate and aamino-5-methyl-3-hydroxyisoxazolone-4-propionate (AMPA) subclasses of ionotropic glutamate receptors. Although it is well established that AMPA receptors mediate fast excitatory synaptic transmission at most excitato

Structure–activity relationships for the

Structure–activity relationships for the analgesic activity of gallic acid derivatives

✍ R Krogh; R.A Yunes; A.D Andricopulo 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 109 KB

The synthesis of 4,5-methano congeners o

The synthesis of 4,5-methano congeners of α-kainic and α-allo-kainic acids as probes for glutamate receptors

✍ Stephen Hanessian; Sacha Ninkovic; Ulrich Reinhold 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 236 KB

The synthesis of diastereomeric 4.5-methano-L-proline 3-acetic acids is described starting from D-serine. The key reactions include a free-radical carbocyclization and an acid-catalyzed destannylative cyclopropanatian of an iminium ion intermediate.

Changes in choline acetyltransferase, gl

Changes in choline acetyltransferase, glutamic acid decarboxylase, high-affinity glutamate uptake and dopaminergic activity induced by kainic acid lesion of the thalamostriatal neurons

✍ Nieoullon, André; Scarfone, Eric; Kerkerian, Lydia; Errami, Mohammed; Dusticier, 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 398 KB

Immunosuppressive structure-activity rel

Immunosuppressive structure-activity relationships of Brequinar and related cinchoninic acid derivatives

✍ Douglas G. Batt; Robert A. Copeland; Randine L. Dowling; Tracy L. Gardner; Eliza 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 321 KB

The immunosuppressive structure-activity relationships of substituted cinchoninic acid derivatives related to Brequinar were explored. Activities as inhibitors of dibydroorotate dehydrogenase and the mixed lymphocyte reaction were related to benzo-ring substitution, replacement of the benzo-ring by