Structural transitions of concanavalin A adsorbed onto bare mica plates: surface force measurements
โ Scribed by J. -P. Gallinet; B. Gauthier-Manuel
- Book ID
- 104655315
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 440 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1432-1017
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โฆ Synopsis
The structure of the/~-sheet rich molecule, con-canavalinA (Con A), shows complicated behaviour when mechanical stress is imposed on adsorbed Con A layers. In the pH range 3.9 to 7.4, the structural changes are dependent on the pH and ionic strength of the solution at the liquid/solid interface. Several molecular shapes are observed ranging from a highly unfolded state characterized by a 1.25 nm thickness of each expelled layer at pH 3.9 to other states with various layer thicknesses at pH 6-7.4 and at a low ionic strength (< 10-4).
In the pH range 6 to 7.4, different molecular species appear to be present.
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