Structural study of 3-methyl-3-azabicyclo[3.3.1]nonan-9-ols functionalized at the 1-position by molecular mechanics calculations and NMR spectroscopy

Synthesis, structural, conformational an

Synthesis, structural, conformational and pharmacological study of esters derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-ol as potential analgesics

✍ I. Iriepa; B. Gil-Alberdi; E. Galvez; J. Sanz-Aparicio; I. Fonseca; A. Orjales; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 1 views

A series of esters derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9a-ol (1) was synthesized and studied by 1 H and 13 C NMR spectroscopy, and the crystal structure of 3-methyl-2,4-diphenyl-9a-(3,5dimethylbenzoyloxy)-3-azabicyclo[3.3.1]nonane (2) was determined by x-ray diffraction. The