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Structural Revision and Total Synthesis of Azaspiracid-1, Part 1: Intelligence Gathering and Tentative Proposal

✍ Scribed by K. C. Nicolaou; Stepan Vyskocil; Theocharis V. Koftis; Yoichi M. A. Yamada; Taotao Ling; David Y.-K. Chen; Wenjun Tang; Goran Petrovic; Michael O. Frederick; Yiwei Li; Masayuki Satake


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
454 KB
Volume
116
Category
Article
ISSN
0044-8249

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Total Synthesis of (+)-Azaspiracid-1. Pa
✍ Davidβ€…A. Evans; Travisβ€…B. Dunn; Lisbet KvΓ¦rnΓΈ; AndrΓ© Beauchemin; Brian Raymer; E πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 341 KB πŸ‘ 1 views

## Dedicated to Professor Dieter Seebach on the occasion of his 70th birthday With a practical synthesis of the ABCD aldehyde in hand (2, Scheme 1), [1] herein we describe our progress that culminated in the synthesis of (+)-azaspiracid-1 (1) in 26 linear steps and 2.7 % overall yield. As outline