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Structural Requirements of Chiral Clofibric Acid Analogs for Activation of the Rat Peroxisome Proliferator-activated Receptor α

✍ Scribed by D. R. FELLER; M. O'BRIEN; S. M. RANGWALA; V. TORTORELLA; F. LOIODICE; D. J. NOONAN


Book ID
111392296
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
126 KB
Volume
804
Category
Article
ISSN
0890-6564

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Enantiomers of a series of substituted analogs of 2-(4-chlorophenoxy) -acetic acid (CPAA) were synthesized and used to examine the influence of steric and structural parameters on peroxisome proliferation. The effects of these compounds were studied on the activation of the peroxisome proliferator-a