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Structural Requirements for Time-Dependent Inhibition of Prostaglandin Biosynthesis by Anti-Inflammatory Drugs

✍ Scribed by Leonard H. Rome and William E. M. Lands

Book ID
123653632
Publisher
National Academy of Sciences
Year
1975
Tongue
English
Weight
533 KB
Volume
72
Category
Article
ISSN
0027-8424

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πŸ“œ SIMILAR VOLUMES

Structural requirements for binding of n
Structural requirements for binding of nonsteroidal anti-inflammatory drugs to human serum albumin
✍ Kim L. Li; Ajit K. Thakur; Amrit L. Kapoor πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 541 KB

The binding of representative chemical classes of nonsteroidal anti-inflammatory drugs (NSAIDs) to human serum albumin (HSA) was investigated by equilibrium dialysis. Warfarin enantiomers were used as specific markers in displacement studies. Data were analyzed by a computerized nonlinear least squa