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Structural requirements for steady-state localization of the vesicular acetylcholine transporter

✍ Scribed by Lucimar T. Ferreira; Magda S. Santos; Natalia G. Kolmakova; Janaina Koenen; Jose Barbosa Jr.; Marcus V. Gomez; Cristina Guatimosim; Xiaodong Zhang; Stanley M. Parsons; Vania F. Prado; Marco A. M. Prado


Book ID
111179008
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
441 KB
Volume
94
Category
Article
ISSN
0022-3042

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The Drosophila vesicular acetylcholine transporter gene (Vacht) is nested within the first intron of the choline acetyltransferase gene (Cha). To isolate Vacht mutants, we performed an F 2 genetic screen and identified mutations that failed to complement Df(3R)Cha 5 , a deletion lacking Cha and the