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Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease Aβ Oligomers

✍ Scribed by Juan Miguel Lopez del Amo; Uwe Fink; Muralidhar Dasari; Gerlinde Grelle; Erich E. Wanker; Jan Bieschke; Bernd Reif


Book ID
116664771
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
967 KB
Volume
421
Category
Article
ISSN
0022-2836

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## Abstract Soluble amyloid β protein (Aβ) oligomers have been considered recently to be responsible for the cognitive dysfunction that sets in prior to senile plaque formation in the Alzheimer's disease (AD) brain. By using the newly prepared antibody against oligomer Aβ, rather than fibrillar or