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Structural principles in cell-cycle control: beyond the CDKs

โœ Scribed by Jane A Endicott; Martin EM Noble


Book ID
114329580
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
170 KB
Volume
6
Category
Article
ISSN
0969-2126

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## Abstract Over 10 years ago, cdk6 was identified as a new member in a family of vertebrate cdcโ€2 related kinases. This novel kinase was found to partner with the Dโ€type cyclins and to possess pRb kinase activity in vitro and has since been understood to function solely as a pRb kinase in the regu