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Structural molecular modelling of the monomer, dimer, trimer and tetramer forms of mannose-binding lectin

✍ Scribed by Ami Miller; Anna Phillips; Russell Wallis; Stephen Perkins


Book ID
116757044
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
84 KB
Volume
45
Category
Article
ISSN
0161-5890

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Dimerization models of c-erbB2 transmembrane domains (Leu651-Ile675) are studied by molecular mechanics and molecular dynamics simulations. Both wild and Glu mutated transmembrane helices exhibit the same relative orientation for favorable associations and dimerize preferentially in left-handed coil