Structural Modifications of Chaparrinone Using Benzeneseleninic Anhydride. Preliminary communication

✍ Scribed by Nguyên Khôi; Judith Polonsky

• Book ID: 102250585
• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: German
• Weight: 246 KB
• Volume: 64
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19810640530

✦ Synopsis

Abstract

Treatment of chaparrinone triacetate with benzeneseleninic anhydride afforded in addition to the Δ^14,15^‐dehydro compound two products arising from angular hydroxylation at C(5). The mechanism of this reaction is discussed. The corresponding deacetylated compounds do not display significant antineoplastic activity.