✦ LIBER ✦

Structural modeling of mutant α-glucosidases resulting in a processing/transport defect in Pompe disease

✍ Scribed by Sugawara, Kanako; Saito, Seiji; Sekijima, Masakazu; Ohno, Kazuki; Tajima, Youichi; Kroos, Marian A; Reuser, Arnold J J; Sakuraba, Hitoshi

Book ID: 120171564
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 649 KB
Volume: 54
Category: Article
ISSN: 1435-232X
DOI: 10.1038/jhg.2009.32

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Chemical chaperones improve transport an

Chemical chaperones improve transport and enhance stability of mutant α-glucosidases in glycogen storage disease type II

✍ Toshika Okumiya; Marian A. Kroos; Laura Van Vliet; Hiroaki Takeuchi; Ans T. Van 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 542 KB

G.P.8.05 The pharmacological chaperone A

G.P.8.05 The pharmacological chaperone AT2220 increases mutant acid alpha-glucosidase levels and reduces tissue glycogen in a mouse model of Pompe disease

✍ R. Khanna; R. Soksa; J. Feng; Y. Lun; A.C. Powe; J. Flanagan; H. Do; D.J. Lockha 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 39 KB

T.P.44 The pharmacological chaperone AT2

T.P.44 The pharmacological chaperone AT2220 increases the stability of recombinant human acid α-glucosidase and leads to greater tissue uptake and glycogen reduction in a mouse model of Pompe disease

✍ Valenzano, K.J.; Feng, J.; Soska, R.; Pellegrino, L.; Frascella, M.; Lun, Y.; Fl 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 60 KB