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Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy

✍ Scribed by Rui, Huan; Kossiakoff, Anthony A.; Im, Wonpil


Book ID
122164211
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
53 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract The MM‐PBSA (Molecular Mechanics–Poisson–Boltzmann surface area) method was applied to the human Growth Hormone (hGH) complexed with its receptor to assess both the validity and the limitations of the computational alanine scanning approach. A 400‐ps dynamical trajectory of the fully so