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Structural Mechanism for Statin Inhibition of HMG-CoA Reductase

✍ Scribed by Istvan, E. S.


Book ID
111675873
Publisher
American Association for the Advancement of Science
Year
2001
Tongue
English
Weight
689 KB
Volume
292
Category
Article
ISSN
0036-8075

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## Abstract This study investigates a proposed design of a peptide sequence that is based on a bioactive conformation of statins that act as the competitive inhibitors of HMG–CoA for HMGR. To bridge these heterogeneous organic compounds, a conformational aspect relating to an analysis of the flexib