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Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2

✍ Scribed by Mario Albrecht; Francisco S. Domingues; Stefan Schreiber; Thomas Lengauer


Book ID
117105983
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
756 KB
Volume
554
Category
Article
ISSN
0014-5793

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As genetic testing for predisposition to human diseases has become an increasingly common practice in medicine, the need for clear interpretation of the test results is apparent. However, for many disease genes, including the breast cancer susceptibility genes BRCA1 and BRCA2, a significant fraction