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Structural Investigation of the Hedamycin:d(ACCGGT)2 Complex by NMR and Restrained Molecular Dynamics

✍ Scribed by Elisabeth A. Owen; Glenn A. Burley; John A. Carver; Geoffrey Wickham; Max A. Keniry

Book ID
115589424
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
125 KB
Volume
290
Category
Article
ISSN
0006-291X

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## Abstract The i‐motif tetrameric structure is built up from two parallel duplexes intercalated in a head‐to‐tail orientation, and held together by hemiprotonated cytosine pairs. Two topologies exist for the i‐motif structure, one with outermost 3β€² extremities and the other with outermost 5β€² extre