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Structural insights into the stereochemistry of the cyclooxygenase reaction

✍ Scribed by Kiefer, James R.; Pawlitz, Jennifer L.; Moreland, Kirby T.; Stegeman, Roderick A.; Hood, William F.; Gierse, James K.; Stevens, Anna M.; Goodwin, Douglas C.; Rowlinson, Scott W.; Marnett, Lawrence J.

Book ID
109769495
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
427 KB
Volume
405
Category
Article
ISSN
0028-0836

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Reductive coupling of ketones to form alkenes, an extremely useful synthetic process in organic chemistry, is most often achieved with the aid of low-valent titanium reagents, according to the procedure developed by McMurry."] It is generally accepted that this reaction involves the intermediacy of