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Structural identification of a key protective B-cell epitope in lyme disease antigen OspA

✍ Scribed by Wei Ding; Xiaolin Huang; Xiaohua Yang; John J Dunn; Benjamin J Luft; Shohei Koide; Catherine L Lawson


Book ID
115630555
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
808 KB
Volume
302
Category
Article
ISSN
0022-2836

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Human leukocyte antigen B27 (HLA-B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is linked to single immunodominant HLA-B27-restricted CD8+ T-cell epitopes in both infections. In order to define the relative contrib