๐”– Bobbio Scriptorium
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Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE

โœ Scribed by Dodani, Sheel C.; Cahn, Jackson K. B.; Heinisch, Tillmann; Brinkmann-Chen, Sabine; McIntosh, John A.; Arnold, Frances H.


Book ID
126230770
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
930 KB
Volume
15
Category
Article
ISSN
1439-4227

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Benzphetamine, an amphetamine with sympathomimetic stimulant activity in the central nervous system, is a substrate for cytochromes P450 with highest metabolic turnover being catalyzed by cytochrome P4502B1. We synthesized three photolabile azido-compound analogs, \(\quad N\)-( \(p\)-azidobenzyl)- \