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Structural features of metallobleomycins bound to DNA

โœ Scribed by David H. Petering; Qunkai Mao; Patricia Fulmer; Eugene DeRose; James D. Otvos; William E. Antholine


Book ID
103570160
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
69 KB
Volume
59
Category
Article
ISSN
0162-0134

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Targeting peptide nucleic acid-protein c
โœ James C. Norton; John H. Waggenspack; Elana Varnum; David R. Corey ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 815 KB

A convenient small scale synthesis has been developed for obtaining peptide nucleic acid oligomers (PNAs). PNAs have been conjugated to a protein, staphylococcal nuclease, through disulfide exchange between a cysteine at the 3'-(carboxy) end of the PNA and an introduced cysteine on the surface of th