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Structural Effects of Carbohydrate-Containing Polycations on Gene Delivery. 3. Cyclodextrin Type and Functionalization

✍ Scribed by Popielarski, Stephen R.; Mishra, Swaroop; Davis, Mark E.

Book ID
118050197
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
154 KB
Volume
14
Category
Article
ISSN
1043-1802

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✍ Alejandro Díaz-Moscoso; Löic Le Gourriérec; Marta Gómez-García; Juan M. Benito; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 592 KB

## Abstract A molecular‐diversity‐oriented approach for the preparation of well‐defined polycationic amphiphilic cyclodextrins (paCDs) as gene‐delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary versus secondary hydroxyl groups on the CD to