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Structural determination of prunusins A and B, new C-alkylated flavonoids from Prunus domestica, by 1D and 2D NMR spectroscopy

✍ Scribed by Azhar Mahmood; Itrat Fatima; Shaheen Kosar; Rehana Ahmed; Abdul Malik

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
103 KB
Volume
48
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

Prunusins A (1) and B (2), the new C‐alkylated flavonoids, have been isolated from the seed kernels of Prunus domestica. Their structures were assigned from ^1^H and ^13^C nuclear magnetic resonating spectra, DEPT and by correlation spectroscopy, HMQC and HMBC experiments. 3, 5, 7, 4′‐Tetrahydroxyflavone (3) and 3, 5, 7‐trihydroxy‐8, 4′‐dimethoxyflavone (4) have also been reported from this species. Both compounds (1) and (2) showed significant antifungal activity against pathogenic fungus Trichophyton simmi. Copyright © 2009 John Wiley & Sons, Ltd.

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