✦ LIBER ✦
Structural determination of aspericins AC, new furan and pyran derivates from the marine-derived fungus Rhizopus sp. 2-PDA-61, by 1D and 2D NMR spectroscopy
✍ Scribed by Fazuo Wang; Tianjiao Zhu; Min Zhang; Aiqun Lin; Weiming Zhu; Qianqun Gu
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 102 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2545
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✦ Synopsis
Abstract
Three new furan and pyran derivatives named aspericins AC (1–3), as well as a known asperic acid (4), have been isolated from the marine‐derived fungus Rhizopus sp. 2‐PDA‐61. The complete ^1^H and ^13^C NMR assignments for the new compounds were carried out using ^1^H, ^13^C, DEPT, COSY, HMQC, HMBC, and NOESY NMR experiments. Compounds 1–3 were evaluated for their cytotoxic activities on P388, A549, HL‐60, and BEL‐7420 cell lines by the MTT and SRB methods. Copyright © 2009 John Wiley & Sons, Ltd.