✦ LIBER ✦
Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata
✍ Scribed by Changhong Huo; Xiaohui Su; Xing Li; Xiping Zhang; Cunfang Li; Yufang Wang; Qingwen Shi; Hiromasa Kiyota
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 130 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2001
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✦ Synopsis
Abstract
A new 2(3 → 20)__abeo__taxane with an unusual 13β‐substitution pattern and a new 6/8/6‐ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β‐diacetoxy‐5α,10β,13β‐trihydroxy‐2(3 → 20)__abeo__taxa‐4(20), 11‐dien‐9‐one (1) and 2α,5α,7β,9α,13α‐pentahydroxy‐10β‐acetoxytaxa‐4(20),11‐diene (2) on the basis of 1D and 2D NMR spectral data and high‐resolution FAB‐MS analyses. Copyright © 2007 John Wiley & Sons, Ltd.