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Structural chemistry and therapeutic intervention of protein-protein interactions in immune response, human immunodeficiency virus entry, and apoptosis

✍ Scribed by Ziwei Huang


Book ID
114129155
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
919 KB
Volume
86
Category
Article
ISSN
0163-7258

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## Abstract The Rev responsive element (RRE), a part of unspliced human immunodeficiency virus (HIV) RNA, serves a crucial role in the production of infectious HIV virions. The viral protein Rev binds to RRE and facilitates transport of mRNA to the cytoplasm. Inhibition of the Rev–RRE interaction d