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Structural Characterization of Human Peripheral Myelin Protein 22 Using NMR

✍ Scribed by Sakakura, Masayoshi; Hadziselimovic, Arina; Sanders, Charles R.


Book ID
122219995
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
64 KB
Volume
98
Category
Article
ISSN
0006-3495

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Peripheral myelin protein 22 (PMP22) is a component of compact myelin of the peripheral nervous system (PNS). Mutations affecting PMP22 are associated with hereditary neuropathies in humans and rodents. Although mammalian PMP22 is expressed in several tissues, the disease pathology is restricted to