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Structural characterization of a methionine-rich, emulsifying protein from sunflower seed

✍ Scribed by Maya J. Pandya; Richard B. Sessions; Phil B. Williams; Christopher E. Dempsey; Arthur S. Tatham; Peter R. Shewry; Anthony R. Clarke


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
414 KB
Volume
38
Category
Article
ISSN
0887-3585

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✦ Synopsis


The 2 S seed storage protein, sunflower albumin 8, contains an unusually high proportion of hydrophobic residues including 16 methionines in a mature protein of 103 amino acids. A structural model, based on the known structure of a related protein, has been constructed as a four-helix bundle cross-linked by four disulphide bonds. This model structure is consistent with data from circular dichroism and nuclear magnetic resonance experiments. Analysis of the model's surface shows the presence of a large hydrophobic face that may be responsible for the highly stable emulsions this protein is known to form with oil/water mixtures.