✦ LIBER ✦

Structural changes in erythrocyte components induced by copper and mercury

✍ Scribed by Krzysztof Gwoździński

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 399 KB
Volume: 45
Category: Article
ISSN: 0969-806X
DOI: 10.1016/0969-806x(94)e0040-p

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✦ Synopsis

The effect of copper and mercury on haemoglobin was studied. Different mechanism of the action of both studied metals on haemoglobin was shown. Action of copper ions on haemoglobin leads to mgnificant changes in its structure. Hg 2+ block---SH groups of globin chains and protect oxyhaemoglobin before the conversion to methaemoglobin. These results suggest that in conversion of oxyhaemoglobin to methaemoglobin thiol groups in the globin chain take part.

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