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Structural basis of the α1–β subunit interaction of voltage-gated Ca2+ channels

✍ Scribed by Chen, Yu-hang; Li, Ming-hui; Zhang, Yun; He, Lin-ling; Yamada, Yoichi; Fitzmaurice, Aileen; Shen, Yang; Zhang, Hailong; Tong, Liang; Yang, Jian

Book ID
109892996
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
748 KB
Volume
429
Category
Article
ISSN
0028-0836

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Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain
✍ Van Petegem, Filip; Clark, Kimberly A.; Chatelain, Franck C.; Minor, Daniel L. 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 394 KB

Voltage-gated calcium channels (Ca(V)s) govern muscle contraction, hormone and neurotransmitter release, neuronal migration, activation of calcium-dependent signalling cascades, and synaptic input integration. An essential Ca(V) intracellular protein, the beta-subunit (Ca(V)beta), binds a conserved