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Structural basis of innate immune recognition of viral RNA

✍ Scribed by Berke, Ian C.; Li, Yue; Modis, Yorgo

Book ID
120942879
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
988 KB
Volume
15
Category
Article
ISSN
1462-5814

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## Abstract Viral infections are detected by sensor molecules, which initiate innate antiviral responses, including the activation of type I interferons (IFNs) and proinflammatory cytokines. These cytokines are responsible for not only inhibiting viral replication in infected cells but also regulat