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Structural basis of cell surface receptor recognition by botulinum neurotoxin B

โœ Scribed by Chai, Qing; Arndt, Joseph W.; Dong, Min; Tepp, William H.; Johnson, Eric A.; Chapman, Edwin R.; Stevens, Raymond C.


Book ID
109896381
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
890 KB
Volume
444
Category
Article
ISSN
0028-0836

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## Abstract ## Objective HLAโ€“B27 is capable of forming in vitro a heavyโ€chain homodimer structure lacking ฮฒ~2~โ€microglobulin. We undertook this study to ascertain if patients with spondylarthritis express ฮฒ~2~โ€microglobulinโ€“free HLAโ€“B27 heavy chains in the form of homodimers and receptors for HLAโ€“