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Structural basis for the specificity of basic winged bean lectin for the Tn-antigen: A crystallographic, thermodynamic and modelling study

✍ Scribed by Kiran A. Kulkarni; Sharmistha Sinha; Samiksha Katiyar; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna

Book ID
116466176
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
342 KB
Volume
579
Category
Article
ISSN
0014-5793

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The crystal structure of the complexes of basic winged-bean lectin with galactose, 2-methoxygalactose, N-acetylgalactosamine and methyl-alpha-N-acetylgalactosamine have been determined. Lectin-sugar interactions involve four hydrogen bonds and a stacking interaction in all of the complexes. In addit

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