𝔖 Bobbio Scriptorium
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Structural basis for the interaction of Ras with RaIGDS

✍ Scribed by Huang, Lan; Hofer, Franz; Martin, G. Steven; Kim, Sung-Hou

Book ID
109964928
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
917 KB
Volume
5
Category
Article
ISSN
1072-8368

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## Abstract In this review, an attempt has been made to throw light on the mechanism of action of colchicine and its different analogs as anti‐cancer agents. Colchicine interacts with tubulin and perturbs the assembly dynamics of microtubules. Though its use has been limited because of its toxicity