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Structural basis for redox regulation of Yap1 transcription factor localization

โœ Scribed by Wood, Matthew J.; Storz, Gisela; Tjandra, Nico


Book ID
109893140
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
342 KB
Volume
430
Category
Article
ISSN
0028-0836

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The genomic materials from some Bacillus subtilis bacteriophages are found to contain 5-(hydroxymethyl)-2'-deoxyuridine in place of thymine. Phage-encoded proteins such as transcription factor 1 specifically and preferentially bind to the minor grooves of these hmU-containing DNA but not to thymine-