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Structural Bases of Unphosphorylated STAT1 Association and Receptor Binding

✍ Scribed by Xiang Mao; Zhiyong Ren; Gregory N. Parker; Holger Sondermann; Michael A. Pastorello; Wei Wang; John S. McMurray; Borries Demeler; James E. Darnell Jr.; Xiaomin Chen


Book ID
116753808
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
715 KB
Volume
17
Category
Article
ISSN
1097-2765

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## Abstract We report here a role for cyclic AMP‐responsive element‐binding protein‐1 (CREB‐1) in B cell antigen receptor (BCR)‐induced growth inhibition by IFN‐γ. BCR‐induced proliferation is negatively regulated by IFN‐γ. Stimulation through BCR resulted in dose‐dependent induction of CREB‐1 bind